Nitric oxide plays an important role in the physiology and the pathophysiology of many organ systems of our body. It is important for many aspects of our health and produced naturally in our body. You can maintain optimal nitric oxide in the body by nitric oxide supplements or with natural ways.

Nitric oxide is important for blood vessels health and important compound for vasodilatation. Nitric oxide helps to relax the blood vessel´s inner muscles. Widen muscles of blood vessels improves blood circulation and lowers blood pressure.

The best rated Nitric Oxide Supplements 2019 are listed below:

  1. Nitrosurge Pre Workout Supplement by Jacked Factory
  2. BulkSupplements L-Arginine a-Ketoglutarate (AAKG) Powder
  3. HEART 360 Nu-Life Supplements
  4. Muscle X Boost- Premium L-Arginine Formula
  5. Nitric Oxide Supplement by Zhou Nutrition

Nitric oxide is important for effective and efficient blood flow the organs of the human body and enhance overall health.

Naturally, enzymes of the body break down Arginine (from food such as shrimp, crab, spinach & turkey) to produce nitric oxide. Nitric oxide supplements contain compounds such as Arginine or nitrate, which our body breakdown to produce nitric oxide.  This provides many health and performance benefits.

Best Nitric Oxide Supplements 2019

There are many nitric oxide supplements and we have compiled the list of some the best available in the market. Before you take any supplements it is recommended to consult your doctor before.


Nitrosurge Pre Workout Supplement by Jacked Factory

Nitrosurge is the product by Canadian company jacked factory. According to their packing mix 1 scoop (9 g) in 6-8 oz of water and take 30-40 minutes before workout. It is recommended not to take more than 2 serving which is 18 g in 24 hours period. One serving has L-citrulline (3 g), betaine anhydrous (1.25 g), beta alanine (1.6 g), L-theanine (90 mg), caffeine anhydrous (180 mg), hordenine HCI (25 mg), Theobromine (50 mg) and AstraGin (25 mg).

Nitrosurge have benefits such as increase of endurance and power. Improve in blood circulation and focus as well as help in fat loss. This nitric oxide supplements effectiveness and affordable pricing make are one of the best in the market.

It comes in two flavors, cherry limeade, and watermelon.

On the downside, it has artificial sweeteners and flavors and low amount of citrulline.

BulkSupplements L-Arginine a-Ketoglutarate (AAKG) Powder

This supplement by BulkSupplements contains 500 grams of AAKG (L-Arginine a-Ketoglutarate) powder. This nitric oxide supplement enhances nitric oxide levels of body and helps to provide nutrients to your muscles. It is recommended to not take this supplement for more than 80 consecutive days.

This supplement has clean and pure AAKG powder and no fillers. They come in the factory-sealed foil zip pouch and are lab-tested for guaranteed purity. According to manufacturer recommended dosage is 2600 mg (1 teaspoon) on an empty stomach up to 3 times a day.

HEART 360 Nu-Life Supplements

HEART 360 by Nu-Life supplements contains the blend of amino acids, L-citrulline, and L-Arginine for nitric oxide production in the body.

This supplement has the number of benefits such as improved blood circulation, muscle development and increases energy. 

This nitric oxide supplement comes in strawberry-kiwi flavor and manufacturer provides 30 days money back guarantee. 

Muscle X Boost- Premium L-Arginine Formula

This nitric oxide by muscle X boost has L-Arginine and L-Citrulline to fuel nitric oxide production.

It helps to improve performance for the workout by giving enough power and fuel.

Nitric Oxide Supplement by Zhou Nutrition

This Nitric Oxide Supplement consists of ingredients such as L Arginine, AAKG, Citrulline Malate, and Beet Root. All these ingredients boost your performance by giving more stamina, and energy.

This nitric oxide supplement by Zhou nutrition is gluten-free and non-GMO. They come in the pack with 120 capsules. According to the manufacturer, you can take 4 capsules in 1 serving, 30 minutes before workout. It is also recommended to take the maximum of 2 serving in a day.

Zhou nutrition also has 30 days money back guarantee if you are not satisfied with the results of this product.

What are nitric oxide supplements?

As we discussed nitric oxide is essential for human body health and performance. That’s the reason why in supplement categories today, nitric oxide supplement is most popular.  Inadequate nitric oxide in the body is often associated with diabetes, erectile dysfunction, and heart disease.

There are natural ways to increase production of nitric acid in the body which we mentioned below.

The optimal level of nitric oxide in the body is essential for overall health. If with natural way your body is not able to produce required nitric oxide, then nitric oxide supplement may help you.

Nitric oxide supplement doesn’t have nitric itself. Instead, they contain amino acids L-citrulline and L-arginine or nitrate. Our body uses these compounds to produce the nitric oxide.

Please consult your health care professional before using nitric oxide supplements.

Nitric oxide supplements benefits

There are lots of studies done on nitric oxide in the last 20 years. Nitric oxide plays the essential roles in the way our body cells communicate with each other.

Some of the benefits of nitric oxide supplements are as following

Heart disease

Most nitric oxide supplements contain amino acid arginine which is used by our body to produce Nitric oxide. It helps blood vessels to relax and improve circulation as nitric oxide is a powerful neurotransmitter.

Improved blood circulation in arteries of the heart can be beneficial for coronary artery disease, clogged arteries, and angina.


People with type 2 diabetes are unable to produce the optimum level of nitric oxide. There are many complications of diabetes such as stroke, kidney failure, and heart disease. This happens because of poor vessel health and accumulation of fatty deposits in the arteries.

According to a study, researchers found that Nitric oxide supplements can enhance nitric oxide production in body and help in diabetes treatment and disease prevention.

It also helps in better sugar control as it increases insulin sensitivity.

Although until future research is done it is premature to conclude the effect of nitric oxide supplements in the treatment of diabetes.

Blood pressure

High blood pressure can cause health issues such as kidney failure and heart disease over time. High blood pressure means pressure on your arteries by force of blood pushing against blood vessels wall is higher than it should be.

There are many factors which can cause high blood pressure or hypertension. Physical inactivity, diabetes, overweight, high cholesterol, unhealthy food, and smoking are some of the reasons.

Nitric oxide supplements help blood vessels to dilate and relax. Improved blood circulation thereafter helps to lower the blood pressure.

Diets which are high in fruits and vegetables help in decreasing blood pressure. Also, beetroot and Dark leafy greens like spinach are good for blood pressure. They contain nitrate which our body uses to produce nitric oxide.

Exercise performance

Nitric oxide helps blood vessels to relax and improves blood circulation. Wider blood vessels enhance the flow of nutrition and oxygen to the working muscles. It therefore boosts and enhances the performance of working muscles during exercise.

Nitric oxide supplements contain ingredients such as amino acids L-arginine or nitrate. They are used by our body to increase nitric oxide. These supplements are nowadays very popular among athletes’, gym goers, swimmers, runners, and cyclists.

If you are taking nitric oxide as performance enhancer then choose the one with nitrate or L-citrulline. As L-arginine, is broken down more quickly as compared to others.

Erectile dysfunction

Production of nitric oxide with nitric oxide supplements which contain amino acid L-citrulline may help in the treatment of erectile dysfunction.

Nitric oxide relaxes the muscles and improves blood circulation in chambers inside the penis.

Researchers found that L-citrulline is less efficient but safer than Viagra which is prescribed the drug for erectile dysfunction.

Nitric oxide supplements which include L-citrulline, L-arginine, and Pycnogenol (plant extract from the pine tree) have shown the promising result for ED.

Muscle soreness

Muscle soreness can occur after strenuous exercise. This uncomfortable soreness usually feels strongest after 24-72 hours of exercise.

Nitric oxide supplements can increase the blood to active muscles which increase nutrient delivery. It also clears waste product such as ammonia and lactate which causes muscle fatigue.

The amount of dosage and exercise you perform can affect the ability of nitric oxide supplement. Further research is needed to determine the effect of nitric oxide for muscle soreness.

Nitric oxide supplements side effects

Nitric oxide supplements are considered safe to use with minor side effects up to 3 months.

Since our body naturally produces nitric oxide it is recommended to take only the appropriate amount. It is recommended to consult the doctor before if you are taking any other medication to lower blood pressure or to treat erectile dysfunction.

If you are pregnant or nursing then never take any supplements before consulting your doctor first.

Some minor side effects of nitric oxide supplements are as following

  • Bloating and abdominal pain
  • Gout
  • Diarrhea
  • Dark red colored urine or stool if your nitric oxide supplement has beetroot juice.

Increase nitric oxide in the body naturally

Nitric oxide is compound which our body produces naturally. As discussed before they are essential for overall health and wellbeing.

There are many natural ways to ensure that your body maintains the optimal level of nitric oxide.


Vegetables are generally healthy for you and vegetables with high nitrate are an excellent source for your body to produce nitric oxide. When nitrate-rich vegetables are consumed our body converts nitrate into nitric acid.

Consuming nitrate-rich vegetables have many health benefits such as lowering blood pressure and improving exercise performance.

Some of the common vegetables high in nitrate are:

  • Spinach
  • Celery
  • Lettuce
  • Beetroot
  • Cress
  • Arugula


Exercise is a good way to improve health. Exercise improves endothelial function which keeps blood vessels healthy. With exercise thin layer of cells inside blood vessels produces nitric oxide. Without insufficient nitric oxide production in the body, there is the risk of many health problems.

With regular exercise, you can improve the nitric oxide production in less than 10 weeks.


Our mouth has many kinds of bacteria’s, some of them are beneficial. Mouthwash helps you in reducing the growth of cavities by killing all oral bacteria. In this process, we lose beneficial bacteria’s too. There are certain bacteria’s which are needed to convert nitrate to nitric oxide.

According to research on the use of mouthwash, it kills bacteria’s needed for nitric oxide for up to 12 hours.


Nitric oxides quickly degrade in blood steam as they are unstable molecules. Antioxidant limits the breakdown and increases the stability of nitric oxide.

Antioxidants need to extend the life of nitric oxide in your body is found in vegetables, fruits, seeds, nuts, and grains.

Some important antioxidants are:

  • Vitamin E: This antioxidant keeps the immune system strong. Free radicals in the body contribute to disease and aging. Vitamin E helps to protect cells from these free radicals.
  • Vitamin C: It helps the body to form connective tissues such as tendons, cartilage, bones, and skin.
  • Glutathione: It is naturally produced in the liver and naturally found in fruits, vegetables, and meat. Glutathione is needed for tissue repair and building, for the immune system and for making proteins needed in the body.
  • Polyphenols: This category of antioxidants has many potential health benefits. They are known for their effectiveness in combating cell damage.

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